Liver flukes are a serious parasitic threat to alpacas that all owners should be aware of. These flatworms have a complex lifecycle and can cause significant disease in alpacas. Left untreated, liver flukes can even be fatal. However, with proper education on identification, prevention, and treatment, alpaca owners can protect their animals. This article will provide a comprehensive overview of liver flukes in alpacas to equip owners with the knowledge needed to safeguard their herd.
What are Liver Flukes?
Liver flukes are a type of parasitic flatworm, known scientifically as trematodes. There are many different species of liver flukes, but the most common types to infect alpacas are Fasciola hepatica and Fascioloides magna. These liver flukes have complex 3-stage lifecycles involving multiple hosts.
Adult flukes live in the bile ducts and liver tissue of infected animals like alpacas, sheep, and cattle. Here they lay eggs that are passed out of the host through the feces. Once in the environment, the eggs hatch and release miracidia larvae which must infect a suitable snail intermediate host species.
Inside the snail, the miracidia undergo several developmental stages ultimately emerging as cercariae. These leave the snail and encyst on vegetation as metacercariae which are then consumed by grazing animals. The metacercariae migrate from the intestine to the liver, maturing into adult flukes where the lifecycle repeats.
The entire process takes about 4-7 weeks, allowing infections to rapidly build within a herd.
Transmission & Lifecycle
Liver flukes have an indirect lifecycle relying on intermediate hosts to transmit the infection. Alpacas become infected by inadvertently consuming metacercariae encysted on plants and vegetation while grazing. Standing water or wet areas favor the growth of these intermediate snail hosts, increasing pasture contamination.
The lifecycle begins when adult flukes in the bile ducts lay thousands of eggs daily, which passes out in the feces:
- Eggs – Pass out in feces and hatch in the environment into miracidia larvae
- Miracidia – Infects snail intermediate hosts like Lymnaea or Galba species
- Undergoes asexual reproduction in the snail
- Cercariae – Exit the snail and encyst on plants as metacercariae
- Metacercariae – Infective stage consumed by grazing alpacas
- Immature Flukes – Migrate from intestine to liver and mature into adults
- Adults – Lay eggs and the cycle repeats
This complex lifecycle makes liver flukes challenging to control but also offers multiple targets for strategic prevention and treatment.
Signs & Symptoms
Liver flukes can cause significant disease in alpacas, but symptoms may be non-specific making diagnosis difficult:
- Weight loss
- Decreased wool production
- General ill-thrift despite a good diet
- Anemia
- Edema under jaw, abdomen, and brisket
- Diarrhea
- Liver enlargement and fibrosis
Heavily infected alpacas may show signs of liver failure including photosensitization, fever, jaundice, hemorrhages, and abdominal fluid accumulation. Sudden death can occur in acute infections.
However, most alpacas exhibit gradual, non-specific decline allowing considerable damage before infection is identified. Subclinical disease lowers productivity and increases susceptibility to other problems.
Diagnosis
Given the non-specific nature of signs, diagnostics are needed to confirm liver fluke infection:
- Fecal testing – Microscopic examination of feces for fluke eggs
- Fluke egg counts – Quantifies severity of infection
- Necropsy – Visualizing flukes in bile ducts of deceased alpacas
- Serology – ELISA blood tests detect antibodies against liver flukes
- Biochemistry – Elevated liver enzymes support diagnosis
- Ultrasound – Can visualize thickened bile ducts and liver changes
Fecal testing is most widely available but may miss prepatent infections before egg laying begins. Serology provides increased sensitivity but both fecal and antibody levels correlate poorly with actual fluke burden.
Postmortem examinations are the gold standard but limited by necessity to deceased alpacas. Ultrasound and biochemistry lend supporting evidence to identify affected animals. Multiple diagnostic modalities in parallel maximize detection rates.
Prevention Strategies
Preventing infection through fluke control measures is key given the insidious damage liver flukes cause:
Snail Control
- Drain or fence off swampy areas to reduce snail habitat
- Apply molluscicides like copper sulfate or hydrated lime to kill snails
- Introduce snail predators such as ducks or fish into water sources
- Rotate wet grazing areas to allow desiccation of snails
Reducing snail numbers curtails availability of intermediate hosts to propagate the fluke lifecycle. However, snails often inhabit large areas making control impractical.
Pasture Management
- Avoid grazing wet areas during high risk seasons
- Prevent livestock access to stagnant water sources
- Rotate grazing areas to allow desiccation of metacercariae
- Delay reintroduction of animals to high risk pastures for 2-3 months
- Provide clean water troughs away from wetlands
- Periodically drag or harrow pastures to disrupt lifecycle
These measures reduce exposure to metacercariae and limit reinfection from contaminated environments. Requires vigilance given fluctuating environmental conditions.
Quarantine & Testing
- Quarantine and screen incoming animals using fecal exams and serology
- Isolate and test sick alpacas
- Cull animals with high fluke burdens
- Autopsy dead alpacas to assess fluke status
Biosecurity is key to prevent introduction from infected herds. Alpaca shows should require proof of parasite monitoring.
Vaccination
- Two commercial liver fluke vaccines for sheep are available
- Reduce disease severity but do not prevent infection
- Effectiveness in alpacas has not been established
Vaccines help mitigate damage from acute fluke infections but do not replace other control measures. Further alpaca-specific research is needed.
By combining multiple preventive strategies, owners can break the complex fluke lifecycle and reduce risk. However, additional treatment is still needed in endemic areas.
Medications & Alternative Remedies
Several conventional and natural treatment options are available once infection is identified:
Anthelmintics
- Triclabendazole – Only drug effective against all stages
- Clorsulon – Treats mature flukes but not early stages
- Albendazole, Oxyclozanide – Varied efficacy in alpacas
Triclabendazole is considered the drug of choice but may require compounding from sheep or cattle formulations. Supportive care for anemia and liver damage may also be warranted.
Minerals & Nutritional Aids
- High zinc and copper supplemental feeds
- Milk thistle to help repair liver damage
- Probiotics and gastrointestinal protectants
- Iron injections, B12, and folate for anemia
- Ensure adequate protein intake
Adequate nutrition and micronutrients support healing and recovery. Must be used alongside conventional deworming.
Natural Dewormers
- Garlic, pumpkin seeds, pineapple have traditional anthelmintic use
- Diatomaceous earth abrasive effects on parasites
- Essential oils like oregano or cinnamon mulled in water
Anecdotally may reduce shedding but insufficient evidence for efficacy against liver flukes in alpacas specifically.
Vaccination
- Cysticercus tenuicollis tapeworm vaccine disrupts fluke lifecycles
- Not OTC – obtain from veterinarian or agriculture department
- Annual booster required approximately 4 weeks before fluke season
Off-label vaccine developed for sheep shows promise in also controlling liver flukes but optimal protocol requires research in alpacas.
Combining conventional and alternative approaches helps attack infection from all angles. Work with your veterinarian to develop a customized, multi-modal treatment plan.
Impacts on Alpaca Health
Liver flukes can have devastating impacts on the health and productivity of a herd if left unchecked:
Reduced Growth & Wool Production
The constant damage to the liver and blood loss into the intestines robs the body of nutrients needed for growth and wool production. Severely infected alpacas often have poor body condition and decreased fiber quality.
Impaired Reproduction
The demands of pregnancy put additional strain on already taxed bodily resources. Heavily infected dams may abort, give birth to small crias, fail to breed, and have decreased milk production.
Increased Susceptibility to Other Diseases
The chronic immune activation and liver impairment caused by liver flukes reduces the ability to fight off other infections. Co-infection with liver fluke often worsens prognoses for diseases like tuberculosis or toxoplasmosis.
Occasional Acute Disease & Death
Sudden death from acute liver damage and hemorrhage may occur in peracute infections where large numbers of migrating flukes destroy liver tissue.
Cost of Treatment & Diagnostics
Dealing with liver flukes requires ongoing testing, proactive herd health programs, and medications or supportive therapies – all of which gets expensive. Preventing infection is far more economical.
Liver flukes silently sap the health and productivity of alpacas. Left unchecked, their insidious damage can cause substantial loss and compromise animal welfare.
Protecting Your Alpacas from Liver Flukes
By understanding the parasitic lifecycle of liver flukes, alpaca owners can implement targeted prevention and control strategies. Consistent testing and surveillance enables early identification of infection alongside strategic use of conventional and natural treatment options.
Guarding against introduction by quarantine and biosecurity is essential. But in endemic areas, an integrated approach combining pasture management, snail control, nutrition, and appropriate anthelmintic treatments offers the best protection. Working closely with your veterinarian to monitor herd health and liver status is key to sustaining productivity.
While challenging to control, liver flukes do not have to spell disaster for an alpaca herd. Education and vigilance empower owners to break the parasite lifecycle and keep their alpacas thriving fluke-free into the future. With proactive effort and commitment to their wellbeing, our alpaca companions can continue living healthy lives by our sides.
